Never say never when it comes to fantasy football lineup decisions -- every roster-worthy player can be started in the right situation. However, when facing tough decisions you should err on the side of caution with the following players this week.
Carson Palmer, QB, Arizona Cardinals at New Orleans Saints
New Orleans' defense has stepped up their play in this young season, and Palmer could be in for a long outing. He very well may be without his best offensive weapon in wide receiver Larry Fitzgerald (hamstring). New Orleans has the offense to force Palmer to have to play catch-up, which may not sound bad at all, but he could wind up tossing several interceptions along the way. Expect roughly 280 yards, one touchdown and at least two interceptions from the vet.
C.J. Spiller, RB, Buffalo Bills at New York Jets
New York has been surprisingly stout against the run so far in 2013, holding opponents to a mere 2.6 yards per attempt on the ground. The Jets have been equally as impressive at suppressing backs in the receiving game, too. They've allowed a mere five receptions for eight total yards in two contests. Start Spiller but do not expect to be gushing about his Week 3 performance around the water cooler on Monday.
Trent Richardson, RB, Indianapolis Colts at San Francisco 49ers
Despite what T-Rich says about being ready to roll this week, he is on the road against the 49ers and has three days to learn a playbook. The Colts likely will use him in very basic offensive formations and situations in Week 3. It is tough to expect them to put him in pass protection. I'd rather take my chances elsewhere, but if you must start him, Richardson has an outside chance of running in a short touchdown.
Josh Gordon, WR, Cleveland Browns at Minnesota Vikings
Fresh off a two-game suspension, Gordon returns to a terrible situation. Cleveland's offense looks nothing like it did before he left. Brandon Weeden (thumb) is on the mend, giving way to quarterback Brian Hoyer, at least for the short term. Gordon is a deep threat and will suffer from Hoyer's mediocre arm. Running back Trent Richardson is now an Indianapolis Colt, which means defenders don't have to play honestly against the run. Sit Gordon.
Julian Edelman, WR, New England Patriots vs. Tampa Bay Buccaneers
Looking for 13 catches again, PPR owners? Lower that number, perhaps by 50 percent or more. If he faces Darrelle Revis, it could be a quiet day for the newfound PPR powerhouse. Don't be surprised if Edelman sneaks one into the end zone, though, because of his nifty route-running skills.
Cecil Shorts, WR, Jacksonville Jaguars at Seattle Seahawks
It looks like Shorts will once again be catching passes from Chad Henne after the duo connected on eight hookups last Sunday. That's the good. The bad is Seahawks standout cornerback Richard Sherman stands in his way from another respectable day. Shorts probably won't be good for more than four or five grabs in Week 3.
Jason Witten, TE, Dallas Cowboys vs. St. Louis Rams
The ultra-athletic linebacking corps of the Rams has done a masterful job of limiting the position this year, holding tight ends to just six total standard fantasy football points in two outings. Witten is always a must-start in PPR leagues, but you might want to look elsewhere in standard formats when he takes on St. Louis.
David Akers, PK, Detroit Lions at Washington Redskins
This game could be a high-scoring affair, featuring a lot of extra point attempts and few field goal tries. Akers can be cast to your waiver wire in favor of a better matchup (look for Rob Bironas, for example).
Green Bay Packers, DST at Cincinnati Bengals
Cincy's defense deserves praise, but their offensive line might warrant more credit. This group has allowed just one sack of Andy Dalton (he took 46 last year) and has turned over the ball three times in two games. Keep the Pack on the pine this time out.